N1-(5-ハロゲノピリミジニル)スルファニルアミド誘導体の合成
1972 年 92 巻 3 号 p. 288-298
詳細
1972 年 92 巻 3 号 p. 288-298
A series of 5-halogenopyrimidinylsulfanilamides (I), possessing methyl, alkoxy, and/or alkylthio groups in the pyrimidine ring, were prepared from the corresponding N4-acetyl derivatives (II) by alkaline hydrolysis. Most of II were prepared from N4-acetyl-pyrimidinylsulfanilamide derivatives by halogenation with NBS or NCS, and the effect of substituents in the pyrimidine ring upon the halogenation reaction was clarified.
