Synthesis and Antibacterial Action of 3-(5-Nitro-2-furyl)-benzo-1, 2, 4-triazine Derivatives

Abstract

Phenylhydrazone and para-substituted phenylhydrazones of 5-nitrofurfural were subjected to coupling reaction with diazonium salts and the resulting formazan derivatives (II) were treated with sulfuric acid to give some benzotriazine compounds (III). Of these compounds tested, the benzotriazine derivatives, IIIa, IIIb, and IIId, showed relatively intense antibacterial activities.