抄録
As one of the quantitative analyses of microquantity of medical drugs by atomic absorption spectroscopy, we attempted the synthesis of o- and p-aminobenzenesulfonamide (p-SA) complexes with Zn, Cu, and Ni and found that o-SA binds in a 2 : 1 ratio with Zn, Cu, and Ni, while p-SA complexes indicate the binding ratio of 2 : 1 for Zn and Cu, and 1 : 1 for Ni. From their infrared analyses, the metal in the o-SA metal complexes was assumed to combine with the nitrogen atom in the sulfonamide group and the amino group attached directly to the phenyl group. However, in the case of p-SA-metal complexes with Zn or Cu, the amino group was considered to be the main binding site to the metals, with a weak bonding through the nitrogen atom in the sulfonamide group.
