Vitali-Freeman Reaction with Benzenoid Compounds

Abstract

Nitrated products of Vitali-Freeman color reaction were investigated. It was concluded from the analytical results of the nitrated products of benzene derivatives in Vitali-Freeman condition that they can be clasified into two groups ; one was colored by their mononitrated product with tetraethylammonium hydroxide (TEAH), and the other, by their polynitrated product. In the nitration of atropine and hyoscyamine, seven compounds were separated by the chromatographic method, and their structures were investigated.