Synthetic Studies of the Flavone Derivatives. II. Synthesis of Cirsimaritin

Abstract

Oxidation of 2'-hydroxy-4-benzyloxy-4', 5', 6'-trimethoxychalcone or 4'-benzoyloxy- 5, 6, 7-trimethoxyflavanone with selenium oxide gave 4'-benzyloxy-5, 6, 7-trimethoxyflavone which, after debenzylation, was partially demethylated with aluminum chloride to give 4', 5- dihydroxy-6, 7-dimethoxyflavone (cirsimaritin).