抄録
Various 1, 3-substituted 6-cyanouracils (IIIa-g, IVa-g) were prepared by the reaction of the corresponding 5-bromouracils (Ia-g, IIa-g) and sodium cyanide in dimethyl formamide or 50% aqueous ethiol. In this reaction, treatment of 1, 3-disubstituted 5-bromouracils (IIa-g) with sodium cyanide in 50% aqueous ethanol, afforded 1, 3-disubstitued 6-carbamoyluracils (Va-g). Antibacterial activity of these compounds in vitro was tested.
