Studies on the Chemical Constituents of Rutaceous Plants. XXXIII : The Chemical Constituents of Xanthoxylum arnottianum MAXIM. (3). Isolation of the Chemical Constituents of the Bark of Root and Stem

Abstract

The chemical constituents of the bark of Xanthoxylum arnottianum MAXIM. (Japanese name : Iwa-Zansho) were examined. Six known alkaloids ; chelerythrine (1) chloride, des-N-methylchelerythrine (2), oxychelerythrine (4), and decarine (12), arnottianamide (9), skimmianine (23), and a new alkaloid, iwamide (13), mp 271-273°, were isolated. Two lignans, l-asarinin (5) and l-sesamin (22), two coumarins, marmesin (6) and columbianetin (24), and eight neutral compounds, arnottin I (7), arnottin II (8), β-amyrin (15), acid X-I (17), sesquiterpene mixture I (11), compound I (10), compound II (14), and compound III (21), were also isolated.