Studies on Isolation of naturally Occurring biologically Active Principles. IV. Antifungal Constituents in the Bark of Hibiscus syriacus L.

Abstract

As one of studies on isolation of naturally occurring biologically active principles, antifungal constituents in the bark of Hibiscus syriacus L. were examined. Two active principles, oil (A), and (B), mp 156-157°, C₁₄H₈N₂O, were isolated by a suitable combination of counter-current distribution and column chromatography. It was found that A was a mixture of lauric, myristic, and palmitic acid, and B was canthin-6-one (6H-indolo [3, 2, 1-d, e] [1, 5] naphthyridin-6-one).