ヘテロ環化合物の研究(第34報)Furo[3,2-c]pyrazole誘導体の合成その2 1,3-Diphenylfuro[3,2-c]pyrazoleの求電子置換反応
1978 年 98 巻 2 号 p. 204-209
詳細
1978 年 98 巻 2 号 p. 204-209
Bromination of 1, 3-diphenylfuro [3, 2-c] pyrazole (I) by equimolar bromine occurred preferentially in the 5-position of the furo [3, 2-c] pyrazole ring, as do Vilsmeier formylation and Friedel-Crafts acyaltion of I. However, nitration of I by acetyl (nitric acid-acetic anhydride) at 0° occurred preferentially in the para and ortho positions of 1-phenyl group to yield 1-(p-nitrophenyl)-3-phenylfuro [3, 2-c] pyrazole and 1-(o-nitrophenyl)-3-phenylfuro-[3, 2-c] pyrazole.
