YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
ピリダジノン誘導体の研究(第6報)4,5-Diethoxy-2-methyl(and phenyl)-3-(2H)-pyridazinoneのアルカリおよび酸との反応
高谷 昌弘山下 武彦小瀬木 幸司
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1978 年 98 巻 4 号 p. 413-417

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Reactions of 4, 5-diethoxy-2-methyl (and phenyl)-3 (2H)-pyridazinone (I) with sodium ethoxide, 10% aqueous sodium hydroxide, and 47% hydrobromic acid were investigated. In some cases, the preferential displacement of 4-ethoxy group by hydroxyl group was observed, indicating that the displacement on the 3 (2H)-pyridazinone ring is affected by the nature of substituent at position 2, reaction species, and the medium enployed.

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