論文ID: JJID.2017.397
The spread and establishment of Chandipura virus (CHPV) infection in India has raised serious epidemiological concerns. Virus interface with the vertebrate hosts, humans and vector competence are the important parameters of disease prevalence. Interestingly, in the present study a highly zoophilic species of sandfly Sergentomyia is emerging as a potential vector of CHPV in Gujarat. It is probably the first report from India that male sandflies have been found to be positive for CHPV by RT-PCR. These finding signifies the vertical transmission of the virus among sandflies and has epidemiological significance.
Health Officers, Gujarat, referred nine pools comprising 277 adult sandflies from the disease affected and non affected areas to National Institute of Virology, Pune. Pools were subjected to RT-PCR and sequencing. Of the nine, two female and one male pool was positive for CHPV. Phylogenetic analysis showed similarity of new sandfly borne CHPV strains to the human strain from Andhra Pradesh (AP) 2003. Present study highlights the possible role of Sergentomyia spp. in the transmission of CHPV in the country.
