Endocrine Journal
Our official Japanese journal "Naibunpigaku Zasshi" was first issued in 1925 and renamed as "Nihon Naibunpigaku-kai Zasshi" in 1927. In 1954 the first issue of English official journal "Endocrinologia Japonica" was published continuing to Volume 39 in 1992 and then renamed as the present "Endocrine Journal" from Volume 40 in 1993.

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Published by The Japan Endocrine Society  
6,801 registered articles
(updated on February 18, 2025)
Online ISSN : 1348-4540
Print ISSN : 0918-8959
ISSN-L : 0918-8959
1.9
2023 Journal Impact Factor (JIF)
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Featured article
Volume 72 (2025) Issue 2 Pages 131-148
Role of radiologists in the diagnosis and management of adrenal disorders Read more
Editor's pick

Recommendation from the Editor in Chief
Radiographic diagnosis and therapeutic approach are requisite for clinics of endocrinology, especially for a series of adrenal diseases. From the unique standpoint of proficient radiologist, Dr. Oguro and colleague contribute a comprehensive and extensive review article focusing on this issue with a particular emphasis on segmental adrenal venous sampling (SAVS) and radiofrequency ablation for the treatment of unilateral primary aldosteronism (PA), shedding light on the importance of collaborative approach toward intractable endocrine diseases.

Volume 72 (2025) Issue 1 Pages 23-36
A narrative review of long-term inorganic iodine monotherapy for Graves’ disease with a historical relationship between iodine and thyroid Read more
Editor's pick

Recommendation from the Editor in Chief
It has been well recognized that inorganic iodine persistently suppresses thyroid function in some cases with Graves’ disease, and can be introduced as an alternative for patients with adverse events on antithyroid drugs. However, scientific bases are not fully elucidated and still remains empirical. In this issue, Dr. Natsuko Watanabe, an editorial board member of Endocrine Journal (EJ), contributes a well-organized, insightful narrative review focusing on this issue. The editorial team of EJ has a firm belief that all readers will be fascinated by an implicative “historical tale” around the relation between iodine and thyroid.

Volume 71 (2024) Issue 12 Pages 1103-1123
Osilodrostat treatment in patients with Cushing’s disease of Asian or non-Asian origin: a pooled analysis of two Phase III randomized trials (LINC 3 and LINC 4) Read more
Editor's pick

Recommendation from the Editor in Chief
Ethnicity-dependent differences in drug responsiveness have attracted broad attention also in endocrinological science. In this issue, Dr. Akira Shimatsu and Professor Beverly MK Biller at Massachusetts General Hospital, an active member of international honorary editors of Endocrine Journal, contribute an insightful original article focusing on ethnicity-related impact of oral 11beta-hydroxylase inhibitor, Osilodrostat between patients with Cushing’s disease of Asian and non-Asian origin. In comparison with non-Asians, Asian patients required apparently-lower doses of the drug to achieve clinical benefits, whereas adverse events related with hypocortisolism were manifested in Asians. As authors stated, this study is the first to compare the impact of drug therapy for patients with Cushing’s disease between Asian and non-Asian origin. Although ethnicity-dependent differences in bioavailability of the drug would be involved, elucidation of the entire picture is strongly anticipated.

Volume 71 (2024) Issue 11 Pages 1093-1096
Snap diagnosis of fulminant type 1 diabetes by the normalized glucose/HbA1c ratio Read more
Editor's pick

Recommendation from the Editor in Chief
It is well recognized that patients with fulminant type 1 diabetes (FT1D), originally characterized by Professor Imagawa and Hanafusa et al, require expeditious diagnosis and successive intensive care. Inspired by the notion that incidence of FT1D in Caucasians has been extremely rare as compared to Asians, Dr. Mori and colleague propose the index beneficial for the snap diagnosis of FT1D in the November issue. Such a valuable suggestion is strongly anticipated to save lives of previously-undiagnosed FT1D worldwide.

Volume 71 (2024) Issue 10 Pages 1003-1011
Cushing’s disease with twin pregnancy and diabetes mellitus: a case report and literature review Read more
Editor's pick

Recommendation from the Editor in Chief
Dr. Hideyasu Asai and colleague report in the October issue an extremely rare case of a pregnant woman with twins suffering from Cushing’s disease, exemplifying hypercortisolism, hypothyroidism and diabetes. After the successful spontaneous vaginal delivery, she received a transsphenoidal surgery, resulting in partial mitigation of hypercortisolism and complete normalization of thyroid function, possibly via the cancellation of cortisol-driven suppression of TSH as well as conversion of T4 to T3. This in-depth case report on a rare situation coupled with pregnancy and hyper ACTH in circulation provides us with fresh insight into elaboration of endocrine networks throughout the body.

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