The purpose of this study was to clarify the influence of pain on physical functions, activities of daily living (ADL), and physical and mental symptoms before and after exercise therapy in patients with cancer undergoing chemotherapy and radiotherapy. Ninety-two patients with cancer were divided into two groups according to the absence or presence of pain (painless group; n = 35, painful group; n = 57, respectively). Physical function, ADL, anxiety, depression, and fatigue were evaluated at the start of exercise therapy and at the time of discharge. The analysis revealed that walking speed, Functional Independence Measure, and anxiety significantly improved after exercise therapy in the painless group. In the painful group, knee extensor strength, walking speed, ADL, anxiety, and fatigue improved significantly, and the degree of pain tended to be lower after exercise therapy. These findings indicate that pain is not an inhibitor of exercise therapy, and it is speculated that exercise therapy can improve physical functions, ADL, and physical and mental symptoms in patients with cancer.
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