The purpose of this study was to clarify the difficulty that nurses have at the end of life in patients undergoing hematopoietic stem cell transplantation (HSCT). Semi-structured interviews were conducted with 10 nurses, and the contents were analyzed qualitatively and descriptively. As a result, five categories were identified: “Ambivalence to support for patients dying during the treatment period”, “Difficulty in supporting the decision making during the patients end of life”, “Feeling of insufficiency and sense of helplessness in which nursing support for patients”, “Difficulty of assistance to families suffering in care of the dying patient”, “Difficulty in coordinating roles among patients, families, and healthcare professionals”.

At the end of life for patients undergoing HSCT, nurses suffered from ambiguity between treatment and end-of-life and difficulty in supporting decision-making. And they were looking for better care. On the other hand, nurses feld it difficult to completely relieve the patient's pain and not be able to fully reflect on the care they were providing. And they were accumulating unfulfilled emotions.