The purpose of this study was to investigate how closing the tympanic membrane perforation for chronic perf orative otitis media (COM) changes the air volume of the middle ear space. High resolution computerized tomography scan of the temporal bone (HRCT) with axial section was obtained in 12 cases of COM before and 18 or more months after myringoplasty. The slice width and thickness were 2 mm. With digital image processing described by Isono in 1994, the air volume of the middle ear space on HRCT was divided in to several planes, the volume of each of which was calculated separately. The sum of the partial volumes yielded the total volume of the middle ear space. The results were as follows 1) The postoperative air volume of the total middle ear space was larger than the preoperative volume (1.44±1.15 ml [Mean±S.D .] and 1.18±0.96 ml, respectively ; n=12). 2) The postoperative air volume of the tympanic cavity was larger than the preoperative volume (0.38±0.07 ml and 0.36±0.10 ml, respectively ; n=12). 3) The postoperative air volume of the mastoid cavity was larger than the preoperative volume (1.06±1.12 ml and 0.82±0.93 ml, respectively ; n=12). 1)-3), statistical analysis of the correlation between the preoperative and postoperative volumes indicated a significant difference (p<0.05). 4) All five cases without preoperative aditus aeration could not attain any aeration of the mastoid cavity postoperatively, either. We interpret the results to mean that, once the tympanic membrane perforation was closed, the middle ear space became normalized and its mucosa swelling improved. In addition, it was aerated again by ventilation through the Eustachian tube and its mucosa. On the other hand, we consider that the aditus mass in the five cases without any aditus aeration was organized and thus obstructed the aeration route to the mastoid cavity.
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