Iontophoresis (IOP) is a noninvasive method of delivering medication transcutaneously through the skin. The electrodes used in this method should tightly fit to rough and irregular surfaces and be biologically safe, easy to handle and prepare, and cost-effective. To satisfy these requirements, calcium alginate gel can be a candidate electrode for IOP. Using calcium alginate gel electrodes, we examined whether lidocaine can be effectively transported across an excised rat skin by squarewave alternating current (AC) application. A squarewave AC with either a 70 % or 80 % duty cycle was continuously applied to 0.5 % calcium alginate gel electrodes containing 10 % lidocaine at 10 V and 1 kHz for 60 min. Lidocaine concentration was measured using a spectrophotometer and the temperature of the gel was determined. The lidocaine concentrations for AC-IOP at the 70 % and 80 % duty cycles were significantly higher than that without AC-IOP. Furthermore, the group with the 80 % duty cycle showed higher lidocaine concentrations than the group with the 70 % duty cycle. The temperatures of all the groups were lower than 28 ℃ throughout the procedure. In conclusion, the calcium alginate gel can be used as a possible matrix for IOP electrodes.

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This study analysed the perceptions of dental clinical attire among patients, dentists and dental students at the Dental Hospital, Tokyo Medical and Dental University using factor analysis to investigate what kinds of factors would underlie the perceptions and would guide evaluation of wearing items of dentist. The subjects comprised 146 patients, 97 dentists, and 81 students of the Dental Hospital. Using a five-point Likert scale, the subjects were asked to score their preferences for 35 items that might be worn by a dentist in the clinic. These scores were analysed using factor analysis and seven factors were extracted. The factors were classified into three categories; the first was a traditional factor representing the public self of dentists, next was casual factors representing the private self of individual dentists, and the other was practical factors. Using MANOVA and univariate ANOVA, differences in perceptions among the subjects were found for factors of casual items while that for traditional items not (P< 0.05). Thus, clinical attire would be evaluated from the viewpoint of interplay between public self and private self of the clinician as well as practical aspects. The variation in perceptions would be influenced by wearers’ gender and observers’ age.

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