The oxidation process of methyl linoleate mixed with methyl octanoate, laurate or palmitate at the molar ratio of 1:1 was measured at 65℃. Methyl linoleate with methyl octanoate was oxidized most rapidly, and the oxidation of the substrates mixed with methyl laurate and palmitate followed. Methyl linoleate was mixed with methyl laurate at the molar ratios of 1:3, 1:1 and 3:1, and its oxidation processes were measured. The methyl linoleate mixed at the lower ratio (1:3) was the most retarded. The oxidation processes were well simulated based on the kinetic equation of the autocatalytic type in consideration of the independent evaporation of methyl octanoate, laurate or palmitate.