In manufacturing the product, the risk is generated with the function, the performance, and the cost at the design stage, too. Then, it is important to plan the risk forecasting when designing. However, measures do not often succeed. The design engineer should feel the responsibility of the influence on the society for the solution of this problem. This is the one that is called "Engineering ethics". The curriculum of the university and Technical College of 80% is the engineer ethics. However, work and the cost give priority if the student enters the enterprise. As a result, it will give priority to the responsibility from the responsibility to the society to the company. And, the engineer ethics are made a ruin, and the disaster cannot be prevented. This is a blind spot of safety. It thinks about the following as a method of settlement. The system that can practice the ethics action is made no consideration of the engineer of ethics. Authors propose ethics based engineering as the example.

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Cardiovascular diseases such as atherosclerosis and cerebral aneurysms are caused by the degeneration of blood vessel wall, which is initiated by hemodynamic forces, particularly wall shear stresses. Therefore it is important to simulate the blood flow and the blood vessel wall as well as the interaction between them. In order to achieve a realistic in-vivo simulation, modeling of appropriate boundary conditions is a crucial issue. The aim of the present research is to develop a numerical simulation system, which considers the interaction between the blood flow and the blood vessel wall of the middle cerebral artery using finite element method, as well as the effect of the peripheral vessels network of the cerebral arteries. The peripheral vessels network was modeled using coupling multi-scale model of 1D and STI (Structure Impedance Model), and then applied as outflow boundary condition to the 3D simulation of patient specific model.

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