In human medicine, the risk of occupational exposure to anticancer drugs is well recognized, and standard procedures have been developed to ensure the safety of healthcare workers. However, little is known in veterinary practice about exposure risk awareness and safe handling of anticancer drugs. In this study, members of the Japan Veterinary Cancer Society answered a survey about anticancer drug exposure and handling. From 213 valid responses, over 90% of the participants understood the risks of anticancer drug exposure and took at least partial measures to prevent it. However, most only wore gloves and masks, with only 19.5% and 11.7% reporting the use of safety cabinets and closed-system drug transfer devices, respectively. Additionally, 95.7% of the respondents expressed concern about exposure risk, and 94.4% indicated a need for continuous education about this issue. Our results show high awareness and concern about anticancer drug exposure risk among veterinarians, highlighting the need to establish appropriate safety measures.

Transitional cell carcinoma (TCC) of the bladder is the most common urinary tract tumor in dogs, and its surgical treatment may involve partial or total cystectomy. Recently, an increasing number of cases of canine bladder TCCs have been reported using en bloc resection of the bladder and urethra, aiming to prevent a high recurrence rate. Here we report a case of canine TCC, which was first treated with en bloc resection of the bladder and urethra to the opening of the external urethral meatus, since no apparent vaginal tumor invasion was observed in the preoperative cystoscopy. However, surgical resection of the uterus, vagina, and vulva was later performed since histopathology revealed tumor invasion of the resected margin, on the urethral side. After the second surgery, histopathology revealed no tumor cells in any resection margins, suggesting the complete resection.