In this study, we present a new numerical method simulating blood flow. In pathologic physiology, it is important to investigate property of blood flow because various organopathy is closely related to disorder of blood flow in microcirculation. In the blood flow simulation, narrowness of blood vessel in microcirculation requires considering size of an erythrocyte. Interactions between plasma and an erythrocyte and between erythrocytes are evaluated by using FDM(Finite Difference Method)for plasma modelling and DEM(Discrete Element Method)for erythrocytes modelling. The present method can evaluate the shear stress acting on each erythrocyte, although it is difficult to evaluate it in experiment. In order to confirm the validity of the method, we simulate the blood flow of two-dimensional straight and bending blood vessels and compare velocity profile with experiment result.
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