Cancerous‐region enhancement using gadolinium‐oxide(Gd
2O
3)suspension and 7.0‐T magnetic resonance imaging is described. The suspension consists of the saline and the Gd
2O
3 nanoparticles with an average diameter of less than 15nm. Six glass vials are filled with six‐different Gd densities of 0, 10, 20, 50, 100 and 200μg/ml. Utilizing T1‐weighted imaging(T1WI), the signal intensity(image density)of Gd media seldom varied with changes in the Gd density. However, the signal intensity decreased with increasing Gd density utilizing T2*‐weighted imaging(T2*WI). The minimum‐detectable Gd density was approximately 20μg/ml, and the minimum‐detectable Gd molar density of approximately 120 n mol/ml was higher than that of Fe in ferucarbotran colloid for liver‐cancer imaging. Subsequently, the signal intensity of the VX2‐cancer region around the cancerous milk in a rabbit thigh decreased by the femoral‐vein injection of the Gd
2O
3 suspension utilizing T2*WI. The VX2 is a popular rabbit cancer sold at laboratory‐animal breeding companies. After seven days from the injection, we observed the Gd
2O
3 nanoparticles remained in the cancerous region.
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