Sera were collected frome 90 patients with herpes zoster, including 35 paired samples, and complement fixing antibody titers were examined. In half of the cases, the titers began to rise in 5 to 7 days, and in all cases in 7 to 9 days after the appearance of the skin eruption.
They reached at their maximum in 2-3 weeks and decreased gradually afterwards (Fig.1, 2).
CF antibodies showed significant increase and decreased slowly in severe and generalized cases when compared to mild and medium cases (Fig. 2, 3).

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The nail plate of the 1st toe of the healthy human and of a patient with yellow nail syndrome have been investigated using color difference meter.
The normal nail plate was cut along the onychodermal band and the dorsal surface of the tip of the plate was examined at 3 different sites after dried in the decicator.
The results are a little bit different after the individuals and sites on the nail plate. If the nail becomes moisty, lighthess and green color are increased but its saturation and yellow color are decreased. When the plate becomes one nineth in its thickness, Saturation, green and yellow color are decreased, whereas its lightness stays unchanged. In yellow nail syndrome, lightness, saturation and green color become increased.

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Histological studies were made with serial sections of papular lesions in five patients with lupus miliaris disseminatus faciei (LMDF) and two with rosacea of epitheloid cell granuloma type.
In the whole seven specimens, a follicle was seen at the center of the granuloma. In the entire five specimens of LMDF, a follicular keratinous cyst surrounded by the epithelial call granuloma was found, and a caseous necrosis was present just below a keratinous material, which had a direct contact with the caseous necrosis in the four cases, and a destroyed thin wall remained between them in one case. In addition, no evidence to support that the patients with LMDF were tuberculosis, was found either clinically or in clinical examinations. Thus the presented patients with LMDF are considered to be rosacea of granulomatous type. The presence of follicular keratinous cysts, that is follicular milia, must be a characteristic feature of rosacea of LMDF type. The formation of caseous necrosis would be ascribed to a direct contact of epitheloid cell granuloma with follicular keratinous materials.

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Intraepidermal mast cells were observed in the phigoid, electron microscopically. The literatures lesions of Sutton's leukoderma and bullous pem- on this phenomenon were reviewed.

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[in Japanese]

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