Annual Meeting of the Japanese Society of Toxicology

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Poster presentations

Development of an Abraded Skin Model in Microminipigs and a Comparison with Rats and Rabbits

Shunsuke Saito, Yoshihiro Takahashi, Tadafumi Motokado, Yuji Sasaki, H ...

Session ID: P-91
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20091.0

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A Four-Week Repeated Dose Percutaneous Toxicity Study of Capsaicin in Microminipigs

Yusuke YAMASHITA, Yoshihiro TAKAHASHI, Tadafumi MOTOKADO, Shunsuke SAI ...

Session ID: P-92
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20092.0

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A Study of Phototoxicity in Pigmented rats

Shinji Utsunomiya, Yoshihiro Takahashi, Kana Oishi, Ryuichi Imada, Shu ...

Session ID: P-93
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20093.0

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Ophthalmological study on retinal atrophy caused by L-glutamate in immature rats

NAOMI SAITOH

Session ID: P-94
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20094.0

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Autonomic nervous system influences on the corrected QT intervals in common marmosets

Masaki Honda, Ryuichi Komatsu, Takehito Isobe, Yukihito Miura, Tatsuya ...

Session ID: P-95
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20095.0

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Usefulness of a telemetry system to measured cardiac contractility in cynomolgus monkeys

Hiroizumi Yamanaka, Kazuaki Sasaki, Yuuji Kuroda, Shigenori Enoki, Ken ...

Session ID: P-96
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20096.0

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Evaluation of cardiac hypertrophy in rats using echocardiography

Katsuyuki Kazusa, Takafumi Shirakawa, Syoko Kida, Daisuke Sasaki, Ayan ...

Session ID: P-97
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20097.0

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Evaluation of left ventricular systolic and diastolic functions by cardiac ultrasonography in cynomolgus monkeys

fumiyuki nakane, yoshinori ishiyama, toshihito kadota, yasuki akie

Session ID: P-98
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20098.0

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Utility of the Microminipig as an animal model for evaluating drug-induced QT-prolongations

Koichi Kuwano, Daisuke Matsushita, Tomoko Hirayama, Tadafumi Motokado, ...

Session ID: P-99
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20099.0

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Testicular gene expression profiling in 1, 3-dinitrobenzene treated ras

Takuya Matsuyama, Noriyo Niino, Naoki Kiyosawa, Kiyonori Kai, Atsushi ...

Session ID: P-100
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20100.0

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Evaluation of reproductive function in male cynomolgus monkeys

KENSUKE MIZUYOSHI, SHUKO SAKAKI, KENSEI MOTOKAWA, HIROFUMI MINOMO, YAS ...

Session ID: P-101
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20101.0

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A laparoscopic investigation study for the effects of levonorgestrel on the ovaries and those specific to the day of ovulation in cynomolgus monkeys.

Koji Fukuda, Shuzo Koyama, Sakae Kohara, Akihiro Arima, Yasuhiro Uno, ...

Session ID: P-102
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20102.0

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The effects of Piperonyl butoxide (PBO) on the female reproductive organs in rats

SEIGO HAYASHI, YOSHIKAZU TAKETA, KAORU INOUE, MIWA TAKAHASHI, SAORI MA ...

Session ID: P-103
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20103.0

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Effects of Sodium Valproate (VPA) on synthesis of ovarian steroidal hormones in rat cultured ovarian follicles

Hiroshi Inada, Kazuhiro Chihara, Chiharu Fukuda, Akihito Yamashita, Yu ...

Session ID: P-104
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20104.0

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Changes of bone parameters induced by feed with differences in Ca and V.D₃ contents

Satoshi Tsuji, Yukari Orihara, shunsuke Tsutsumi, Yoshinobu Iwaki, Rie ...

Session ID: P-105
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20105.0

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Background data for electrocardiogram in juvenile beagles

Hisako HORI, Toshiya ISHII, Hajime ABE, Akihiro UMEDA, Hiromi SUZUKI, ...

Session ID: P-106
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20106.0

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Background data for hematological and blood chemical examinations in juvenile beagles

Toshiya ISHII, Hisako HORI, Makoto ISHIGAMI, Hiroyasu MIZUGUCHI, Dai W ...

Session ID: P-107
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20107.0

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Effects of repeated intravenous dosing operation on the inflammation parameters in cynomolgus monkeys

Kana ISHIHARA, Ryo TAKAI, Tatsuya ITO, Ryouta SAITO, Toshiko HARA, Tak ...

Session ID: P-108
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20108.0

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Clinicopathological Examination in Micro Mini Pigs

Yoshiyuki Suzuki, Hiroyuki Saito, Takayuki Kubota, Miyuki Takao, Kumik ...

Session ID: P-109
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20109.0

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Historical data of carcinogenicity studies in RccHan^TM:WIST rats

Atsuko MIKI, Maki AIMI, Satomi HASHIMOTO, Yuki TOMONARI, Atsushi IWAI, ...

Session ID: P-110
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20110.0

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Cuprizone, a copper chelating agent, induces iron-deficiency like anemia.

Mariko Tomita, Sayuri Kojima, Naofumi Takahashi, Katsumi Soma, Masayuk ...

Session ID: P-111
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20111.0

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Hepatic cytochrome P450 gene expression analysis in developmental stages of cynomolgus monkeys

Ryota Ise, Satoshi Kondo, Hiroto kato, Noritaka Imai, Hideo Akiyama, Y ...

Session ID: P-112
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20112.0

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An Immunological Response Assessment to KLH Immunization in Infant Cynomolgus Monkeys

Satoru Oneda, Narine Lalayeva, Rebecca Watson, Patricia Lin, Hideshi T ...

Session ID: P-113
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20113.0

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Effects of phenylenediamine on the male reproductive organs in mice

Kuniaki Tayama, Yoshimitsu Sakamoto, Hiroshi Ando, Yoshikazu Kubo, Hir ...

Session ID: P-114
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20114.0

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Effect of PPARd agonist on Rat Placenta

Kyohei Nishimura, Nao Fukumoto, Ryou Fukushima, Atsuko Hishikawa, Masa ...

Session ID: P-115
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20115.0

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Experimental Study of Cleft Palate in Rats Treated with Sterol Biosynthesis Inhibitor

Takafumi OHTA, Naoki IKEMI, Shinya SHIMAZU, Ryuji YOSHIDA, Kunio KAWAS ...

Session ID: P-116
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20116.0

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Comparison of postnatal data between Wistar Hannover (RccHan^TM:WIST) and SD rats

EISUKE KIMURA, RYUJI YOSHIDA, HIROYUKI IZUMI, HIDEAKI HIRATSUKA

Session ID: P-117
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20117.0

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Comparison of embryo-fetal development data between Wistar Hannover (RccHan^TM:WIST) and SD rats

Ryuji Yoshida, Eisuke Kimura, Hiroyuki Izumi, Hideaki Hiratsuka

Session ID: P-118
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20118.0

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Effects of in utero exposure to indomethacin on the closure of the ductus arteriosus in neonatal rats.

Mitsuyuki Shirai, Eri Takenoshita, Fumitoshi Asai, Motoharu Sakaue, Ma ...

Session ID: P-119
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20119.0

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Study about anesthetization of fetuses with transplacental treatment of pentobarbital sodium

Mika SENUMA, Yuka YOSHIDA, Makiko KUWAGATA, Kensuke ORITO, Koichi IMAI ...

Session ID: P-120
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20120.0

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Morphological evaluation of sperm in rat exposed to Dibromochloropropane by utilizing the dark field images in the computer-assisted sperm analysis

Katsumi Ohtani, Shigeru Yamazaki

Session ID: P-121
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20121.0

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A Trial of Breeding by The Artificial Insemination in Synchronized Ovulation Phase of Cynomolgus Monkeys

Shuzo Koyama, Koji Fukuda, Sakae Kohara, Akihiro Arima, Yasuhiro Uno, ...

Session ID: P-122
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20122.0

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Investigation of the strain differences between Sprague-Dawley and Wistar Hannover rats in bone marrow micronucleus test

yukari terashima, kazuo kobayashi, ryohei yokoi, ikuro takakura, yoshi ...

Session ID: P-123
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20123.0

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Evaluation of effect of the drug-metabolizing enzyme-inducing agent on the genotoxicity stydies

Yuki Kishino, Mayumi Nagata, Chiharu Hattori, Shingo Arakawa, Tomoko H ...

Session ID: P-124
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20124.0

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Difference of acrylamide-inducing genotoxicity between child and adult in gpt delta male rats

NAOKI KOYMA, MANABU YASUI, AOI KIMURA, SHIGEAKI TAKAMI, TAKUYA SUZUKI, ...

Session ID: P-125
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20125.0

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Prior exposure to organophosphorus and organochlorine pesticides increases the allergic potential of environmental chemical allergens

Tomoki Fukuyama, Yukari Tajima, Koichi Hayashi, Hideo Ueda, Tadashi Ko ...

Session ID: P-126
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20126.0

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Immunotoxicology Study in Rats and Involvement of Safety Pharmacology and Genotoxicity Parameters

Hiroyuki Komatsu, Yoshiyuki Suzuki, Kumiko Kitta, Hiro Eda, Ayano Sueo ...

Session ID: P-127
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20127.0

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Behavioral and metabolome analyses of methamphetamine-induced neurotoxicity in rats

Izuru Miyawaki, Noriaki Shima, Kiyoko Bando, Hiroshi Horie, Takeshi Ba ...

Session ID: P-128
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20128.0

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Effect of methamphetamine on mice under severe stress conditions - One month processing -

Masafumi Tomita, Hironobu Katsuyama, Yoko Watanabe, Toshiko Okuyama, S ...

Session ID: P-129
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20129.0

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Mechanism analysis of genotoxicity using HepG2 cells : analysis of phosphorylation of histone H2A.X and cell cycle using high content analysis system

Masamitsu ANDO, Keisuke YOSHIKAWA, Yumiko IWASE

Session ID: P-130
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20130.0

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Toxicological significance of "a gap between a result of LDH assay (toxic evaluation) and a result of WST-8 assay (functional evaluation)" which is rarely observed in in vitro cytotoxicity test using rat primary cultured hepatocytes

Kazunori Fujimoto, Hiroyuki Kishino, Chieko Ohba, Noriyo Niino, Naoki ...

Session ID: P-131
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20131.0

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In vitro 3T3 NRU phototoxicity test results with 68 drugs: correlation with photosensitivity

Yumiko Iwase, Tatsuya Honda, Yonako Nakajima, Yoshifumi Sasaki

Session ID: P-132
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20132.0

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Investigation of in vitro cytotoxicity and hepatotoxicity using High Content Analysis

Junichiro Saito, Kazuhiko Ikeda, Kenichi Hanioka, Satoru Naganuma, Tak ...

Session ID: P-133
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20133.0

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Seeking Gene Candidates Responsible for Developmental Origins of Health and Disease (DOHaD)

Tetsuo Ogawa, Randeep Rakwal, Junko Shibato, Chika Sawa, Tomomi Saito, ...

Session ID: P-134
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20134.0

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Involvement of Membrane-Bound Glutathione Transferase In Disulfide-Linked Mitochondrial Permeability Transition Pore Caused By Peroxynitrite

Naoki Imaizumi, Yoko Aniya

Session ID: P-135
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20135.0

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Mathematical Modeling of the Apoptotic Pathways Induced by Cisplatin

Ji-Young Hong, Soon-Sung Kwon, Kenjirou Hara, Eisuke Sato, Masayasu In ...

Session ID: P-136
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20136.0

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A proposal of PGC-originated epigenetic toxicity testing.

Tohru Shibuya, Yukiharu Horiya

Session ID: P-137
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20137.0

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Alterations of Creb in the liver induced by phenobarbital sodium

Ryoichi OHTSUKA, Makio TAKEDA, Satoru YAMAGUCHI, Sayuri KOJIMA, Mariko ...

Session ID: P-138
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20138.0

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Age-related changes on fluoride levels in hard tissues of the body in rats

Hajime Tabata, Kazuhito Sakamoto, Hidetomi Kadokura, Hirofumi Minomo, ...

Session ID: P-139
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20139.0

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Isolation and Characterization of a gene encoding paclitaxel transporter from a human breast cDNA library

YASUNA KOBAYASHI, YURIE TAKESHITA, TAKAHIRO UMEMOTO, KENZI HIBI, YUTAK ...

Session ID: P-140
Published: 2011
Released on J-STAGE: August 11, 2011

DOIhttps://doi.org/10.14869/toxp.38.0.20140.0

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