I report on incubated leucocyte infusion therapy for RA patients. Cultured leucocytes are obtained from healthy human leucocytes which are cultivated for 48 hours being added with 5% RPMI-1640. The cultured leucocytes consist of Three types of cells: one, an activated Omikoshi-cell, the other, non-omikoshi cell.
The patient has to be medicated once every 4 weeks, and this is repeated 6 times, comprising 1 course. After initial medication, this course has to be repeated once every 2 to 4 months depending on the patient's recovery. The healing rate is 100% for patients with stage I and II RA.
The main problem associated with this therapy is its high cost, 50, 000yen (approx. $500) for every dosage, and incubated leucocytes have to be infused within 24 hours.
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