The Shokan-Ron (傷寒論) was written for the infectious diseases caused by influenza-virus, typhus-bacillus and dysentery-bacillus which have an affinity for water. Therefore at first the meridional changes of water (衛水) on C.m. yang solaris appear through the extravascular fluid channel.
On the contrary in the Oneki-Ron (温疫論) were written 2 sorts of the infectious diseases caused by air-affinitive bacillus and blood-affinitive virus. The former results from pneumo-coccus, tubercle-bacillus and influenza-virus, which have a strong affinity for air. These bacilli spread out by means of the air, which is separated by membrane (e.g. diaphram). Therefore the disease stays at first in focus superior (the thoracical cavity) accompanied pleurisy and then affects infiltrately (not meridionally) the neighboring organs such as thymus and marrow of sternum which produce blood.
Secondly the changes extend to the left upper abdominal cavity, where exist organ like colon, ventriculus and pancreas which always relate with gas. Then pathological changes spread out infiltrately (not meridionally) the neighboring organs i.e. gall-bladder, portal vein and thoracic duct which are blood organs. Thus complete the changes of focus media (the upper abdominal part).
At last the changes invade into the extraperitoneal organ i.e. kidney (focus inferior) and then attack upon liver-spleen which excrete and catch the destroyed component of blood.
It is interesting that we Occidental physicians used to experience the same course of diseases in tuberculosis.
Besides air-affinitive bacillus, the eruptive infectious diseases such as pocken, measles, scarlatina, fleck-fever and influenza were written in the Oneki-Ron.
These diseases are mainly caused by virus, accompanying bacillemia, and in consequence of the emanation of long continued diseases, remain the sepsis resulting from pyocyaneus-bacillus, streptcoccus and staphylococcus which may be mixedly affected with above-mentioned eruptive infectious virus. These septic bacilli have a strong affinity for blood. In this sepsis, changes advance from the extravascular (meridional) Eiki (衛気) to the intravascular Eiketsu (営血).
Oshukuwa (王叔和) attempted to synthethize the Shokan-Ron (the Kampo-medicine) which occurred in the south of China and the Somon-Reisu (素問霊枢 the acupuncture medicine) in the north. This tendency was more emphasized in the Oneki-Ron.
At any rate I indicate the difference between the Shokan-Ron and the Oneki-Ron from the standpoint of the aer-sanguis-aqua-pathophysiology.
The water-affinitive bacillus invades into the extra-vascular (meridional) fluid channel, the blood-affinitive virus the intravascular one and the air-affinitive bacillus spreads out the neiboring organ generally and infiltrately (not meridionally) by means of
Morely's radiation.
But in the last stage of both types Shokan-Ron and Oieki-Ron appear the liver-spleen diseases which relates with the blood diseases (sepsis) and become the status of Shinkan-Kanetsu (真寒仮熱).
Besides above-mentioned classification in Occidental medicine there is the nerve-affinitive bacillus, e.g. influenza-virus, meningo-coccus, diphtheria-bacillus etc. which have also intimate affinity for air.
Applying the bacillus and virus of acute infectious diseases to the Kampo-medicine I found another contact point of the Occidental and Oriental medicine.
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