We investigated the condition of the liver in a total of 5486 subjects (3889 males and 1597 females) who received adult-disease screening examinations.
The following results were obtained.
1. Fatty liver was found in 13.9% of the males and 3.8% of the females with a male/female ratio of about 3.7 to 1. In males, the prevalence of fatty liver was lower in those in their 20's than in any other age ranks, while there was little difference in the age range from the 30's to the 50's. In females, the prevalence sharply increased in those in their 50's.
2. The percentage of fatty liver increased with the obesity index in both males and females.
3. With respect to alcohol drinking, the prevalence of fatty liver was not affected by the presence or absence of alcohol drinking, the daily drinking quantity and total drinking quantity.
4. Of those screened for adult disease, 14.7% of the males and 2.7% of the females had abnormal liver function, with a male/female ratio of about 5.4 to 1. In both males and females, the prevalence of fatty liver was higher in those who had abnormal rather than normal liver function.

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　2013年に和食がユネスコの無形文化遺産に指定されて以来，海外の醤油の研究や，醤油から原料を拡大した魚醤油，海藻醤油，キノコ醤油，エゴマ醤油といった醤油様調味料の研究の報告が増加傾向にある。また，安全安心への関心の高まりからアレルギー様物質であるヒスタミンに関する研究も増えてきた。今後は，地域ごとの最適化と安全安心がキーワードとなった研究開発が進展するものと期待される。

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