This is a report on the therapeutic experience with 12 cases treated for ulcerative colitis in the Chiba National Hospital during the period of past 10 years.
This series consisted of 7 males and 5 females, and their age distribution varied from 21 to 58 years. Among them, 5 were treated conservatively and the remainder surgically.
The conservative group showed mere up-and-down in symptome, except for one case who responded to Chymoral.
The administration of steroides brought certain improvement postoperatively, but resulted in the recurrence or the leakage from anastomosis in some of them, therefore, this therapy was not applied to the last 5 cases.
There was one death in the operated group.
All the other, however, have rehavilitated to the social or house works postoperatively during the observation periods varying from 2 to 5 years. Of the 4 cases subjected to partial colectomy, one was cured, but the remainder required total colectomy eventually for recurrence. One case treated with permanent ileostomy and total colectomy showed satisfactory results.
The permanent ileostomy does not hinder their social rehabilitation. Therefore, those subjected to conservative therapy ineffectively should be treated with permanent ileostomy and total colectomy in an early stage of this diseas.
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