An antiserum against human thymocytes was prepared in rabbits and absorbed with RBC, aceton liver powder, serum and human B cell line. We investigated the distribution pattern and degree of T cells in tumor tissue using immunoperoxidase technique with ATS. The results obtained in this study might be summarized as follows.
1. A majority of the lymphocytes consisting of T cells was observed along the layer of the tumor margins.
2, There were no significant correlation between the degree of local T cell infiltration and the number of peripheral blood T cells. Therefore, we should pay attention to local lymphocytic distribution when the head and neck malignancy was examined from the immunological point of view.
3. There were no significant correlations between the degree of T cell infiltration in tumor tissue and clinical and laboratry data, i. e, the staging of the tumor, the prognosis of the patients, metastasis, skin sensitivity testing, lymphocytic response to phytohemagglutinin, etc.
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