Michiko Ogawa, Noboru Yamaguchi, Yoshichica Aosaki, and Hiroshi Okubo First Department of Internal Medicine, Kansai Medical school, Moriguchi, Osaka, Japan
Ichiro
Yamagata,
Ichiro
Kuwabara and Sotokichi Morii Department of Pathologx, Kansai Medical School Case 1.40 years old male:
When he was walking, sudd enly attacked by shock syndrome. Clinical diagnosis was myocardial infarction, but autopsy revealed no remarkable infarction in the myocatd. Main pathological changes were severe sclerosis of coronary arteries, atherosclerosis of aorta, nephrosclerosis, atrophy of adrenal glands, hypoplasia of bone marrow and adhesion of pleura.
C ase 2.40 years old male:
Clinical picture was that of waterhouse-Friederichsen synndrome. As the lesion which directly caused the death, a large hemorrhage was found in the ventricular septum of the heart, which compressed the conduction system.
Autopsy revealed atrophy of adrenal glands, although bleeding was not detected there. The other Pathological findings were hypoplasia of spleen, small softening in parietal lobe of the brain and chronic hepatitis.
Discussions were made on the mechanism of shock including the role of adrenal glands, and on the nessecity of precise examinations in such cases.
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