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Characteristics of InAlGaAs/InAlAs Superlattice Avalanche Photodiodes for Ultra-low Optical Power Detection in the Near Infrared

Yasunori SAITO, Tomoyuki MARUYAMA, Hideaki YAMAKI, Fumitoshi KOBAYASHI, Takuya
D
. KAWAHARA, Akio NOMURA, Mitsuyoshi TANAKA

Optical Review
1999年 6 巻 5 号 459-463
発行日: 1999/10/01
公開日: 2000/03/28

DOI https://doi.org/10.1007/s10043-999-0459-8

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Static characteristics of two different structured InAlGaAs/InAlAs superlattice avalanche photodiodes (SLAPDs) cooled by liquid nitrogen were evaluated at a wavelength of 1.
5
μm. The dark current of the SLAPD having a thick superlattice layer of 0.504 μm was
5
×10^-13 A. This was successively reduced by four orders of magnitude compared to that of the thin layer SLAPD of 0.231 μm at a breakdown voltage of around 20 V. The thickened layer was effective in suppressing tunneling dark current. An output current of 1.7×10^-12 A at a bias voltage of 15 V was measured for an optical input with a wavelength of 1.
5
μm and a signal power of 1×10^-12 W. This showed a sharp distinction from the dark current.
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(
22E
, 24S)
5α
-Stigmasta-
3
,
22
-dien-
6
-one: An Intermediate of the Isomerization of (
22E
, 24S)-
3α
,
5
-Cyclo-
5α
-stigmast-
22
-en-
6
-one into (
22E
, 24S)-
5α
-Stigmasta-2,
22
-dien-
6
-one

Suguru TAKATSUTO, Kiyomi KOBAYASHI, Tsuyoshi WATANABE, Hiroki KURIYAMA, Tokuo FURUSE

Agricultural and Biological Chemistry
1988年 52 巻 12 号 3217-3218
発行日: 1988年
公開日: 2006/04/05

DOI https://doi.org/10.1271/bbb1961.52.3217

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GENERALIZED LIMIT EQUILIBRIUM METHOD AND ITS RELATION TO SLIP LlNE METHOD

榎明潔, 八木則男, 矢田部龍一, 一本英三郎

土質工学会論文報告集
1991年 31 巻 2 号 1-13
発行日: 1991/06/15
公開日: 2008/02/29

DOI https://doi.org/10.3208/sandf1972.31.2_1

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It has been shown after mathematical and mechanical investigation that Limit Equilibrium Method (LEM) can be considered as a method to obtain the necessary condition of Slip Line Method (SLM), and that the solution can be obtained under the condition that F_s=1 and ∂F_s/∂θ=O, where F_s is the safety factor and θ is the inclination of the plane on which the safety factor is defined. Next, the generalized LEM (GLEM) is proposed, dealing with the following points : (1) Triangular or quadrangular blocks can be treated; (2) Safety factors are defined also on interblock planes; and (
3
) All types of plastic problems, slope stability, bearing capacity, and earth pressure are identically formulated. Two situations regarding treatment of the moment equilibrium condition are discussed. GLEM is applied to well-known problems. The results agree well with those obtained by theoretical methods. GLEM can be used to obtain the distribution of earth pressure or bearing capacity. GLEM, Iike ordinary LEM, is very effective for the practical problems, but GLEM is more theoretical and it can result in more accurate solutions.
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A PRESSURE AND DENSITY DEPENDENT DILATANCY MODEL FOR GRANULAR MATERIALS

R.G. WAN, P.J. GUO

地盤工学会論文報告集
1999年 39 巻 6 号 1-11
発行日: 1999/12/15
公開日: 2008/02/29

DOI https://doi.org/10.3208/sandf.39.6_1

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This paper outlines a mathematical description of the stress dilatancy behaviour of granular materials which accounts for stress level and void ratio dependencies. The consideration of these aspects has important implications in the modelling of granular material behaviour. In fact, granular material mechanical response is largely dominated by the evolution of dilatancy, fabric and void ratio histories. The starting point in this study is the well established Rowe's theory which is revisited and ultimately modified by introducing a factor linked to governing state parameters in order to describe the complete behaviour of granular materials during deformation. Numerical simulations of triaxial tests on granular materials at different void ratios and stress levels are herein presented to illustrate the model.
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Potential causes of different gastric stability of original and generic proton pump inhibitors

Daria Kurguzova, Svetlana Serebrova, Alexey Prokofiev, Ludmila Krasnykh, Galina Vasilenko, Marina Zhuravleva, Elena Smolyarchuk, Anton Barkov

日本薬理学会年会要旨集
2018年 WCP2018 巻 WCP2018_PO3-5-27
発行日: 2018年
公開日: 2020/09/10

DOI https://doi.org/10.1254/jpssuppl.WCP2018.0_PO3-5-27

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Background
The differences in conditions of enteric-coated acid-labile drug release and absorption between healthy subjects in bioequivalence studies and gastrointestinal patients in clinical practice can lead to significant differences in gastric stability of original PPIs and generics. Thus, pathologic duodenogastric reflux (PDGR) and the pH increasing within PPIs administration still remain unaccounted for.
Methods
Two-stage modified comparative dissolution testing of original omeprazole (OO) and four generics (G1;2;
3
;4) was performed. At first, we moved drugs from solution with pH 1.2 (1.2±0.05) to pH 7.0 (7.0±0.05) and measure concentration of omeprazole in solution by high-performance liquid chromatography. According to our self-developed formula, pH 7 exposure time of resistance to PDGR for omeprazole is 4 minutes, i.
e
. the active substance should not be released within 4 minutes at pH 7. The exposure at the second stage was conducted with pH 4 (4.0±0.05), that imitated gastric pH after PPI administration. And then we also moved drugs to pH 7 with the subsequent measurement of omeprazole concentration.
Results
Omeprazole concentrations after 4, 10, 15, 20, 30, 45, 60 minutes in pH 7 solution at the first stage were different for OO and generics. For OO, these values were 4,7±0,7%; 41,4±
3
,0%; 62,
8
±4,0%; 79,
5
±2,
9
%; 83,
5
±2,
9
%;
81
,
6
±2,
9
%; 80,
6
±4,4%; for Generic1 - 0; 49,
3
±
9
,
9
%;
88
,
8
±2,
8
%; 90,4±
3
,7%;
88
, 2±2,2%; 87,
3
±2,0%; 85,
9
±1,1%; for Generic2 - 0; 30,
6
±
6
,
3
%; 66,7±
8
,2%; 76,4±7,4%;
82
,
8
±
5
,
3
%; 86,0±
3
,7%; 84,
6
±
3
,
3
%: for Generic
3
- 80,
8
±
3
,
6
%; 83,
5
±1,
9
%; 83,
8
±
3
,2%; 83,
3
±2,7%;
81
,
9
±2,1%;
82
,1±2,0%;
82
,0±2,4%; for Generic4 -
82
,
5
±1,7%; 84,4±0,
8
%; 84,2±1,2%;
82
,
9
±0,
9
%;
82
,
9
±0,
9
%;
82
,
9
±0,
9
%;
82
,
8
±1,1%, respectively.
An analysis of the omeprazole concentration in pH 7 solution at the second stage revealed the following parameters after the same time: for OO - 4,4±0,
6
%; 40,
5
±
3
,0%; 62,
8
±2,0%; 80,0±
3
,1%; 85,4±2,
9
%;
82
,
8
±
3
,4%; 80,
9
±
3
,
5
%; for Generic1 - 0; 67,0±7,
8
%; 89,7±2,
3
%;
91
,
9
±4,
3
%; 89,1±1,
6
%;
88
,
3
±1,4%; 87,
8
±1,2%; for Generic2 - 0; 42,2±
5
,
6
%; 75,1±7,
3
%;
81
,0±
6
,0%;
88
,4±
3
,2%;
88
,
6
±1,
3
%; 87,
9
±1,0%; for Generic4 - 85,
5
±0,
5
%; 85,
6
±0,
5
%; 84,7±0,
9
%;
82
,7±
3
,0%; 84,4±0,
3
%; 84,4±0,
3
%; 84,
3
±0,4%, respectively. Generic
3
release and degradation were completely realized at pH 4.
Conclusion
Decreased gastric stability of Generic
3
and Generic4 makes PDGR and inhibited gastric acid secretion due to PPIs administration the potential causes of decreased enteric-coated acid-labile drugs stability.

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日本から,そして海から世界に革命を起こし『持続可能な未来を創る』ためのファーストステップとしてのEV船

末次康将

マリンエンジニアリング
2021年 56 巻 5 号 680-687
発行日: 2021/09/01
公開日: 2021/10/12

DOI https://doi.org/10.5988/jime.56.680

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Stimulative Effects of (
22E
,24R)-Ergosta-7,
22
-diene-
3β
,
5α
,
6β
-triol from Fruiting Bodies of Tricholoma auratum, on a Mouse Osteoblastic Cell Line, MC
3
T
3
-
E
1

Keishi Hata, Fuyuki Sugawara, Naganori Ohisa, Saori Takahashi, Kazuyuki Hori

Biological and Pharmaceutical Bulletin
2002年 25 巻 8 号 1040-1044
発行日: 2002年
公開日: 2002/08/01

DOI https://doi.org/10.1248/bpb.25.1040

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We screened the differentiation-inducing activities of 39 mushroom extracts from Akita prefecture, Japan, on the mouse osteoblastic cell line, MC
3
T
3
-
E
1. Sixteen phosphate buffered saline (PBS),
8
boiled PBS, 14 ethanol and 12 methanol extracts induced alkaline phosphatase (ALP) activities, an indicator of MC
3
T
3
-
E
1 cell differentiation. The enzyme activities were markedly induced by extracts of Tricholoma auratum, and we isolated the active compound from methanol extracts of this mushroom. Physical data for the isolated active compound were identical to those for (
22E
,24R)-ergosta-7,
22
-diene-
3β
,
5α
,
6β
-triol (1). 1 induced ALP activities of MC
3
T
3
-
E
1 cells and promoted cell proliferation. To investigate the relationships between the chemical structure and differentiation-inducing activity of the compound, ALP-inducing activities of MC
3
T
3
-
E
1 cells by 1, ergosterol (2), ergocalciferol (
3
), cholesta-
3β
,
5α
,
6β
-triol (4), 7-dehydrocholesterol (
5
) and cholecalciferol (
6
) were tested. The enzyme activities of MC
3
T
3
-
E
1 cells were increased
3
.0-fold by 10 μM 1 and 2.4-fold by 10 μM 4. However, 2,
3
,
5
and
6
did not induce MC
3
T
3
-
E
1 cell ALP activity at 0.1—10 μM. These results suggested that the OH groups at C-
5
and/or C-
6
of 1 and 4 played an important role in their differentiation-inducing activities on MC
3
T
3
-
E
1 cells. Furthermore, 1 suppressed induction of MC
3
T
3
-
E
1 cell apoptosis by serum starvation.
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A biosynthetic pathway for (
E
)-methyl cinnamate formation in the ectomycorrhizal fungus Tricholoma matsutake

Takefumi Hattori, Hiromitsu Tsuzuki, Hiroe Amou, Kumio Yokoigawa, Masanori Abe, Akira Ohta

Mycoscience
2016年 57 巻 3 号 181-186
発行日: 2016年
公開日: 2023/03/07

DOI https://doi.org/10.1016/j.myc.2016.01.001

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A biosynthetic pathway for (
E
)-methyl cinnamate formation was evaluated in Tricholoma matsutake by tracer experiments using ¹³C- and ²H-labeled precursors. One hundred percent selective ¹³C incorporation was observed when L-[1,2,
3
,4,
5
,
6
,7,
8
,
9
-^{13C₉
, ^15/N]phenylalanine was converted to (E
)-[1,2,3
,4,5
,6
,7,8
,9
-^{13C₉
]cinnamate and (E
)-[1,2,3
,4,5
,6
,7,8
,9
-^{13C₉
]methyl cinnamate. Similarly, 100% selective ¹³C incorporation was observed when (E
)-[1,2,3
,4,5
,6
,7,8
,9
-^{13C₉
]cinnamate was converted to (E
)-[1,2,3
,4,5
,6
,7,8
,9
-^{13C₉
]methyl cinnamate. In contrast, the ²H incorporation selectivities were 82
.1% and 81
.4% when L-[2,3
,4,5
,6
,7,7,8
-^{2H₈
]phenylalanine was converted to (E
)-[2,3
,4,5
,6
,7,8
-²H₇]cinnamate and (E
)-[2,3
,4,5
,6
,7,8
-²H₇]methyl cinnamate, respectively. Thus, T. matsutake synthesizes (E
)-methyl cinnamate from L-phenylalanine via (E
)-cinnamate. (E
)-cinnamate was likely formed through two pathways: one was major and the other was a minor.
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An Efficient Preparation of (
22E
, 24S)-
5α
-Stigmasta-2,
22
-dien-
6
-one from (
22E
, 24S)-
3α
,
5
-Cyclo-
5α
-stigmast-
22
-en-
6
-one

Tsuyoshi WATANABE, Hiroki KURIYAMA, Tokuo FURUSE, Kiyomi KOBAYASHI, Suguru TAKATSUTO

Agricultural and Biological Chemistry
1988年 52 巻 8 号 2117-2118
発行日: 1988年
公開日: 2006/04/05

DOI https://doi.org/10.1271/bbb1961.52.2117

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INSTALLATION TORQUE OF SCREW ANCHORS IN DRY SAND

ASHRAF GHALY, ADEL HANNA, MIKHAIL HANNA

土質工学会論文報告集
1991年 31 巻 2 号 77-92
発行日: 1991/06/15
公開日: 2008/02/29

DOI https://doi.org/10.3208/sandf1972.31.2_77

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The performance of single pitch and multi pitch screw anchors during the application of installation torque is presented. An experimental testing program was conducted using five models of screw anchors with different geometry. The effect of the shape of the screw element, sand properties, and installation depth on the required installation torque value was examined. A theoretical model was developed from which the required installation torque value can be calculated in terms of the influencing factors. The required installation torque can be determined in terms of the ultimate uplift resistance calculated from any of the available theories. Based on the actual installation torque value measured in the field, the anticipated pullout capacity can be back calculated from the present theory. A comparison between theoretical and experimental results showed good agreement. Also, good agreement was observed when the present theoretical results were compared with the available field results reported in the literature.
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男子尿中 Estrogen の測定

R. I.・Ittrich-Fluorometry

田中啓幹

日本泌尿器科學會雑誌
1969年 60 巻 12 号 1125-1142
発行日: 1969年
公開日: 2010/07/23

DOI https://doi.org/10.5980/jpnjurol1928.60.12_1125

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Urinary estrogens have been assayed chiefly with the Kober hydroquinone colorimetry or sulfuric acid fluorimetry. However, it is difficult to determine accurately small amounts of estrogens such as in urines from males, oophorectomized women or menopausal women. In this study, male urinary estrogens were determined by a modification of the method reported by Kambegawa and some experimental studies were made on male urines. 200ml aliquot of 24-hour urine is hydrolyzed by the
3
-step hydrolysis, added with estrone-
6
, 7³H, 17β-estradiol-
6
, 7³H and estriol-
6
, 7³H, and extracted with ether, followed by alkaline washes, methylation by a supersonic wave mixer, thin layer and column chromatography, liquid scintillation spectrometry and the Ittrich fluorometry. Results of experimental studies and estimation of urinary estrogens in males are as follows: 1) After the
3
-step hydrolysis, 54.
5
% of the urinary estrogens were collected as the glucuronide, 30% in the solvolyzed fraction and 15.
5
% as the hot acid hydrolyzate. 2) The methylation of estrogens was achieved 10-20% better by the use of the supersonic wave mixer than by a magnetic stirrer.
3
) Calculating efficiency of the Packard Tri-carb liquid scintillation spectrometer was tested in varieties of the estrogen concentrations using the dilution and the external standardization methods. There was noted no influence of the estrogen concentrations on the counting efficiency in the determination ranges. 4) In the range of 2×10^{-3
-1.0μg, a linear relationship on the standard curve was obtained applying the Allen's correction, when fluorometry was conditioned with the excitation light wave length of 510mμ and the fluorescence wave lengths of 530, 550 and 570mμ for each of the three estrogen-methyl ethers. 5
) Urinary estrogens were determined in 15 normal males. In 5
subjects (2-13 years old) the values were: E₁
: 1.06±1.09; E₂
: 0.64±0.54; E₃
: 0.76±0.68 and the total E
: 2.46±1.99μg/24hr. In 5
men (22
-38 years old), E₁
: 5
.02±1.57; E₂
: 2.58±0.21; E₃
: 4.11±1.82
and the total E
: 11.72±2.97μg
/24hr. In 5
men (46-72 years old), E₁
: 3
.81
±0.31; E₁
: 1.71±0.48; E₃
: 3
.51±0.94 and the total E
: 9
.03±1.33μg/24hr. 6) Urinary estrogens were also determined in patients with a variety of clinical syndromes.
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UPLIFT CAPACITY OF PLATE ANCHORS IN SLOPED CLAYEY GROUND

S.NARASIMHA RAO, Y.V.S.N. PRASAD

土質工学会論文報告集
1992年 32 巻 4 号 164-170
発行日: 1992/12/15
公開日: 2008/02/29

DOI https://doi.org/10.3208/sandf1972.32.4_164

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Plate anchors are the popular type of anchors used in civil engineering construction both on land and offshore. In this paper, the uplift capacity of plate anchor in a sloped clayey ground has been brought out with the help of an experimental programme, carried out on a 50mm diameter model plate anchor. The tests have been conducted at slopes of O°, 15°, 30°and 45°. From the test results, it is found that in the case of shallow anchor, as the slope is increasing from O°to 45°, there seems to be a reduction in uplift capacity. Simple expressions are suggested to arrive at the uplift capacities in sloped ground. The mechanisms involved in the reduction of capacity with slope are explained based on the observed behaviour.
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HOLDING CAPACITY OF INCLINED SQUARE PLATE ANCHORS IN CLAY

BRAJA M. DAS, VIJAY K. PURI

土質工学会論文報告集
1989年 29 巻 3 号 138-144
発行日: 1989/09/15
公開日: 2008/02/29

DOI https://doi.org/10.3208/sandf1972.29.3_138

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Laboratory model test results for the holding capacity of inclined shallow square plate anchors in clay (φ=0 concept) have been presented. The inclination of the anchor with respect to the horizontal was varied from zero to 90°. Based on the model study, an empirical relationship for estimating the ultimate holding capacity of the anchors has been presented.
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Assessing the Optimal Location of Near Side Bus Stop to Enhance Advantages of Bus Signal Priority (BSP)

*Pradeep Kumar SHRESTHA, Fumihiko NAKAMURA, Toshiyuki OKAMURA

Proceedings of the Eastern Asia Society for Transportation Studies
2009年 2009 巻
発行日: 2009年
公開日: 2010/08/25

DOI https://doi.org/10.11175/eastpro.2009.0.234.0

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In this paper, bus signal priority (BSP) with different near side bus stop position in reference to the average queue during red time of the selected intersection and bus detection after bus departure from stop was modeled. Three alternative positions such as bus stop within normal queue, at the end of normal queue and beyond the distance of normal queue were evaluated for traffic flow ratios of 0.7, 0.
9
and 1.1 by simulation method. Two objective functions i.
e
. decrease in delay for priority movement and increase in delay for non-priority movements were considered. Since there are two objective functions, Pareto-optimal situation arises. The optimal case was selected based on the shortest normalized distance to Pareto optimal sets. Bus stop at the end of normal queue outperforms reducing total person delay in priority direction with least increase in total person delay on non-priority direction.
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UNCERTAINTY OF MOBILIZED UNDRAINED SHEAR STRENGTH

W. TANG, G. MESRI, I. HALIM

土質工学会論文報告集
1992年 32 巻 4 号 107-116
発行日: 1992/12/15
公開日: 2008/02/29

DOI https://doi.org/10.3208/sandf1972.32.4_107

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A method for analyzing the uncertainties involving the use of empirical relationships in design is developed. It is applied to evaluate the reliability of the relationship s_u(mobilized)=
0.22σ'_p
(measured), whereby the pertinent uncertainties are analyzed using extensive laboratory and field observed data. On the average, the relationship s_u(mobilized)=
0.22σ'_p
(measured) is unbiased and the error implicit in the relationship is about 15%. When cone values are used to infer s'_p, additional uncertainties on the mobilized undrained strength will incur resulting mainly from the calibration uncertainty between σ'_p and the cone values. Alternatively, vane tests may be performed to infer the mobilized strength using Bjerrum correction factor. Results show that uncertainty level associated with using the vane tests is smaller than that using the cone values, provided that similar scatter is observed between measured vane and cone values at a given site. However, prediction of the mobilized strength is even more accurate if direct measurements can be made on the preconsolidation pressure. The proposed probabilistic method also assesses the benefit of additional tests besides comparing the accuracy of using various soil parameters for predicting mobilized undrained strength. Such information is essential for planning cost-effective site characterization program.
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AN ELASTOPLASTIC MODEL FOR UNSATURATED SOILS UNDER GENERAL THREE-DIMENSIONAL CONDITIONS

M. M. FARIAS, M. PINHEIRO, M. P. CORDAO NETO

SOILS AND FOUNDATIONS
2006年 46 巻 5 号 613-628
発行日: 2006年
公開日: 2011/01/27

DOI https://doi.org/10.3208/sandf.46.613

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Engineering problems concerned either directly or indirectly with unsaturated soils are more and more common, ranging from aspects related to seepage to those related to shear strength and volume change. A few constitutive models have been conceived to describe and quantify these problems all of them with some advantages and drawbacks. Regarding mechanical behavior, the so-called Barcelona Basic Model (BBM) has achieved wide acceptance in geotechnical engineering, basically due to its simple mathematical formulation and good description of phenomena associated with unsaturated soils, especially collapse. Another concept that has emerged as a powerful framework to tackle three-dimensional states in granular materials is that of a modified stress tensor, such as t_ij. In this paper both BBM isotropic structure and t_ij concepts are combined to propose a new elastoplastic model for unsaturated soils, called t_ij-unsat. Modifications and generalizations for unsaturated states are introduced to accommodate those frameworks and overcome some inherited drawbacks. At the end of this work, experimental data gathered from specialized geotechnical literature is used to support the theoretical framework. The satisfactory agreement between simulations and tests results emphasizes the applicability of the proposed formulation to real boundary value geotechnical problems.

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Representations of Unitary Groups and Free Convolution

Philippe Biane

Publications of the Research Institute for Mathematical Sciences
1995年 31 巻 1 号 63-79
発行日: 1995年
公開日: 2009/04/24

DOI https://doi.org/10.2977/prims/1195164791

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III型高脂血症に関する研究

等電点ゲル電気泳動法を用いたアポ蛋白Eの Isoform の検討

上田幸生, 吉村陽, 若杉隆伸, 渡辺彰, 多々見良三, 上田良成, 亀谷富夫, 羽場利博, 小泉順二, 宮元進, 馬淵宏, 竹田亮祐

動脈硬化
1981年 8 巻 4 号 745-751
発行日: 1981/01/01
公開日: 2011/09/21

DOI https://doi.org/10.5551/jat1973.8.4_745

ジャーナルフリー

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According to Utermann et al, Apo
E
is usually separated into three major isoforms, ie
E
1,
E
2,
E
3
, and he reported three phenotypes of Apo
E
, Apo
E
-N, Apo
E
-ND, Apo
E
-
D
, according to the Apo
E
2/
E
3
ratios.
In this study we examined Apo
E
polymorphism by isoelectric focusing and ultracentrifugal lipoprotein analysis in 124 Japanese subjects including
5
patients with primary type III hyperlipoproteinemia.
Following results were obtained.
1) The Apo
E
protein focused into four main bands, Apo
E
1′,
E
1,
E
2,
E
3
(normal pattern) and fifth band (Apo
E
4), (variant pattern).
2) In primary type III hyperlipoproteinemia, Apo
E
3
was deficient, wherease Apo
E
2 and Apo
E
1 increased.
3
) We examined distribution of Apo
E
patterns according to Apo
E
3
/
E
2 ratios in 124 subjects. The distribution of the Apo
E
3
/
E
2 ratios showed a trimodality. All the patients with primary type III hyperlipoproteinemia were in the lowest mode (
E
3
/
E
2 below 0.
3
) which represents Apo
E
-
D
. In the remainders, 34 subjects were in the middle mode (
E
3
/
E
2, between 0.
6
-1.4) which represents Apo
E
-ND. and 85 subjects were in the highest mode (
E
3
/
E
2 above 1.
5
) which represents Apo
E
-N.
These cutoff points correspond to those which Utermann had reported in the German populations. Thus, there were no differences in Apo
E
phenotypes between Japanese and German populations.
4) In
3
patients out of
5
patients with primary type III hyperlipoproteinemia, we measured postheparin lipolytic activity. Two cases (H. N., M. K.) showed a decreased hepatic lipase activity (H-TGL) and a normal lipoprotein lipase activity (LPL).
But one case (S. I.) showed a normal H-TGL and LPL.
5
) VLDL-TC/VLDL-TG and VLDL-TC/whole serum TG ratios were higher in Apo
E
-ND than in Apo
E
-N, and higher in Apo
E
-
D
than in Apo
E
-ND.
These results suggests that Apo
E
3
deficiency had a effect which increases lipoprotein remnants.
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〔41〕タービン入口温度測定のための熱電対, M.
E
. Ihnat & W. C. Hagel, Trans. ASME, Series
D
, 1960-
3
, Vol.
82
, No. 1, p.
81
〜86, 図
5
, 表
3

西村正巳

日本機械学会誌
1961年 64 巻 504 号 193-
発行日: 1961/01/05
公開日: 2017/06/21

DOI https://doi.org/10.1299/jsmemag.64.504_193_2

解説誌・一般情報誌フリー

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E
群色素性乾皮症の
3
例

袋秀平, 近藤靖児, 川田暁, 佐藤吉昭, 藤原美定, 比留間政太郎, 岡村理栄子, 儘田晃, 中山坦子

西日本皮膚科
1987年 49 巻 5 号 801-807
発行日: 1987/10/01
公開日: 2012/03/10

DOI https://doi.org/10.2336/nishinihonhifu.49.801

ジャーナル認証あり

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E
群色素性乾皮症(以下XP)の
3
例を報告した。XP80TO(50才), XP
81
TO(42才), XP
82
TO(41才)のいずれも女子で, XP80TOの両親が従兄妹である以外血族結婚はない。いずれも
5
∼
9
才ごろに日焼けしやすいことに気づいた。XP80TO,
81
TOはそれぞれ46才, 41才のときに顔面に皮膚腫瘍(basalioma)が発生し, 切除術を受けた。臨床的に露光部に粟粒大から大豆大までの色素斑, 脱色素斑を認めるが, 眼症状はみられない。一般臨床検査, 神経学的検査でも異常を認めない。光線テストで, 紫外線紅斑反応のピークはXP80TO,
81
TOでは48時間後, XP
82
TOでは24時間後で, 最小紅斑量(MED)は全例に中等度の低下を認めた。培養線維芽細胞の不定期DNA合成は正常の40∼44%で, また254nm紫外線に対する患者由来細胞の致死感受性はn=1.
3
∼1.
8
,
D₀
=2.2∼2.
8
J/m²であり, これらの値は正常人とA群XP患者の中間に位置した。相補性テストで
3
例とも
E
群と決定した。現在までに報告された本邦の
E
群患者例には血族結婚および皮膚腫瘍の発生はみられないが, 自験例で示されたごとく, 本邦例でも家系内同症や皮膚腫瘍について留意すべきであると考えた。
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