Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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Synthesis of 2-(Pyrimidin-4-yl)indoles
Laura Hernández FrancoJorge Alejandro Palermo
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2003 Volume 51 Issue 8 Pages 975-977

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Abstract

The synthesis of 2-substituted isomers of the meridianins, a familiy of bioactive indole alkaloids isolated from the tunicate Aplidium meridianum, was undertaken. The synthetic route comprises six steps, with a microwave promoted Fischer cyclization as the key reaction.

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© 2003 The Pharmaceutical Society of Japan
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