Molecular and Histological Studies of Pituitary Tumorigenesis Using Experimental Animal Models

抄録

Pituitary tumorigenesis is a complex pathway involving numerous factors and conditions, such as hormonal stimulations, cell cycle regulators, growth factors, and transcription factors. To better understand this disease, to date, several experimental animal models have been established and analyzed. This article reviews and updates the studies on molecular mechanisms of pituitary tumorigenesis which were investigated using experimental model animals.