CYTOCHEMICAL DEMONSTRATION OF CA²⁺-ATPase+IN THE CHOROID PLEXUS OF THE THIRD VENTRICLE

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Ca²⁺-ATPase activity in the choroid plexus of the third ventricle of the rat was cytochemically detected. Reaction products were detected in the apical and basolateral plasma membranes of the choroid plexus epithelial cells. The activity was calcium-dependent in both membranes. High substrate specificity for ATP was observed only in the apical plasma membrane. It is speculated that Ca²⁺-ATPase in the apical plasma membrane acts as a Ca²⁺-pump and regulates cerebrospinal fluid Ca²⁺ concentration.