Analytical Sciences
Online ISSN : 1348-2246
Print ISSN : 0910-6340
ISSN-L : 0910-6340
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Anchoring Transitions of Liquid Crystals for Optical Amplification of Phospholipid Oxidation Inhibition by Ascorbic Acid
Minmin ZHANGChang-Hyun JANG
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2015 年 31 巻 12 号 p. 1329-1333

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There is considerable evidence that the antioxidant property of ascorbic acid (AH) is effective for reducing oxidative stress of phospholipids. Herein, a liquid crystals (LCs)-based method was developed for the optical amplification of resistance to phospholipid oxidation by AH. Phospholipid peroxidation initiated by free radicals was monitored from a homeotropic-to-planar anchoring transition of LCs via polarized optical microscopy. Alternatively, consistent homeotropic anchoring of LCs was observed when the oxidation caused by free radicals was blocked by AH.
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© 2015 by The Japan Society for Analytical Chemistry
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