EURYSTATINS A AND B, NEW PROLYL ENDOPEPTIDASE INHIBITORS
II. PHYSICO-CHEMICAL PROPERTIES AND STRUCTURE DETERMINATION
1992 年 45 巻 10 号 p. 1580-1586
詳細
1992 年 45 巻 10 号 p. 1580-1586
The structures of eurystatins A and B, new prolyl endopeptidase inhibitors, have been elucidated by chemical degradation and spectral studies. They have in common a unique 13-membered cyclic peptide core composed of L-leucine, L-ornithine and (S)-3-amino-2-oxobutyric acid, and differ from each other in the α, β-unsaturated fatty acid attached to the α-amino moiety of the ornithine.
