Argifin, a New Chitinase Inhibitor, Produced by Gliodadium sp. FTD-0668 I. Taxonomy, Fermentation, and Biological Activities

SATOSHI OMURA; NORIKO ARAI; YUUICHI YAMAGUCHI; ROKURO MASUMA; YUZURU IWAI; MICHIO NAMIKOSHI; ANDREAS TURBERG; HEINZ KÖLBL; KAZURO SHIOMI

doi:10.7164/antibiotics.53.603

Argifin, a New Chitinase Inhibitor, Produced by Gliodadium sp. FTD-0668

I. Taxonomy, Fermentation, and Biological Activities

SATOSHI OMURA, NORIKO ARAI, YUUICHI YAMAGUCHI, ROKURO MASUMA, YUZURU IWAI, MICHIO NAMIKOSHI, ANDREAS TURBERG, HEINZ KÖLBL, KAZURO SHIOMI

著者情報

ジャーナルフリー

2000 年 53 巻 6 号 p. 603-608

DOI https://doi.org/10.7164/antibiotics.53.603

詳細

抄録

A new chitinase inhibitor, named argifin, was isolated from the cultured broth of a fungal strain FTD-0668. The strain was identified as Gliodadium sp. from morphological characteristics. The IC₅₀ value of argifin against Lucilia cuprina chitinase was 3.7μM. Argifin arrested the moult of cockroach larvae upon injection into the ventral abdominal part.

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）