This paper describes briefly the results obtained with AMPC(Pasetocin®)administered by oral route to 21 patients with infection of the respiratory tract.
1. There was no difference in therapeutic effect on infection of the respiratory tract between daily dosages of 1,000mg and 750mg(the former was orally given in 4 divided doses every 6 hours a day and the latter in 3 divided doses after meal).The response of the patients to AMPC was remarkable or satisfactory. 2. Acute aggravation symptoms associated with chronic infection of the respiratory tract showed similar improvement to single acuto infection of the respiratory tract. 3. The patients presenting acute aggravation symptoms received treatment for chronic stage consisting of consecutive oral administration of AMPC(500-750mg a day)and their prognosis was favorable.Side effects attributable to prolonged treatment were not noted. 4. The incidence of side effects can be reduced largely by rejecting from AMPC therapy the patients who are hypersensitive to drugs including penicillins.
