Multiple Cytokines-Producing Pleomorphic Carcinoma of Lung with Metastasis to the Small Intestine

Satoshi Hara; Keita Hosoi; Yasuhiko Suga; Tetsuo Takata; Hiroyuki Degami; Yoshinori Kinoshita; Kyongyob Min

doi:10.5761/atcs.cr.13-00202

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Multiple Cytokines-Producing Pleomorphic Carcinoma of Lung with Metastasis to the Small Intestine

Satoshi Hara, Keita Hosoi, Yasuhiko Suga, Tetsuo Takata, Hiroyuki Degami, Yoshinori Kinoshita, Kyongyob Min

著者情報

キーワード: cytokine, pleomorphic carcinoma, lung, G-CSF, TNF-α

ジャーナルオープンアクセス早期公開

論文ID: cr.13-00202

DOI https://doi.org/10.5761/atcs.cr.13-00202

この記事には本公開記事があります。

The final version of this article is now available: Vol. 20 (2014), No. Supplement pp. 666-668

詳細

抄録

A 58-year-old man underwent upper lobectomy for primary pleomorphic carcinoma of the lung. Nine months later, the pleomorphic carcinoma was recurred with marked peripheral leukocytosis and an elevated C-reactive protein. Chest and abdominal computed tomography (CT) revealed enlarged mediastinal lymph nodes and a bulky tumor in the small intestine. An enterectomy was performed and the intestinal tumor was removed. Immunostaining revealed tumor cells positive for G-CSF and TNF-α as well as an increased level of serum G-CSF and TNF-α. We describe a rare case of G-CSF and TNF-α producing pleomorphic carcinoma of the lung with metastasis to the small intestine.

責任著者(Corresponding author)

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