Stereoselective Synthesis of Optically Active Methylene Lactone, Key Intermediate for the Synthesis of 1,2-Oxidized Furofuran Lignan, from L-Glutamic Acid

抄録

  (4R)-[(1S)-1-[(tert-Butyldimethylsilyl)oxy]-1-(2-methoxy-4,5-methylenedioxyphenyl)methyl]-3-methylenedihydro-2(3H)-furanone and (4R)-[(1R)-1-[(tert-butyldimethylsilyl)oxy]-1-(2-methoxy-4,5-methylenedioxyphenyl)methyl]-3-methylenedihydro-2(3H)-furanone, which are key intermediates for the synthesis of 1,2-oxidized furofuran lignan, were each stereoselectively synthesized from L-glutamic acid.