Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Food & Nutrition Science
Glycitein Effect on Suppressing the Proliferation and Stimulating the Differentiation of Osteoblastic MC3T3-E1 Cells
Hiroyuki YOSHIDATakanori TERAMOTOKatsumi IKEDAYukio YAMORI
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2001 年 65 巻 5 号 p. 1211-1213

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Glycitein, as one of the three major isoflavones in soybeans, directly but significantly (about 50%) suppressed the proliferation of MC3T3-E1 and stimulated bone-related protein (alkaline phosphatase (ALP) and osteocalcin (OC)) expression. These results indicate that glycitein suppresses the proliferation of osteoblasts and promotes differentiation from its progenitor.

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© 2001 by Japan Society for Bioscience, Biotechnology, and Agrochemistry
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