Three Antinematodal Diterpenes from Euphorbia kansui

Jian-Xiao SHI; Zhi-Xuan LI; Teruhiko NITODA; Minoru IZUMI; Hiroshi KANZAKI; Naomichi BABA; Kazuyoshi KAWAZU; Shuhei NAKAJIMA

doi:10.1271/bbb.60677

Organic Chemistry Notes

Three Antinematodal Diterpenes from Euphorbia kansui

Jian-Xiao SHI, Zhi-Xuan LI, Teruhiko NITODA, Minoru IZUMI, Hiroshi KANZAKI, Naomichi BABA, Kazuyoshi KAWAZU, Shuhei NAKAJIMA

Author information

Jian-Xiao SHI
The Graduate School of Natural Science and Technology, Department of Biofunctional Chemistry, Laboratory of Applied Natural Products Chemistry, Okayama University
College of Life Science, Northwest University
Zhi-Xuan LI
College of Life Science, Northwest University
Teruhiko NITODA
The Graduate School of Natural Science and Technology, Department of Biofunctional Chemistry, Laboratory of Applied Natural Products Chemistry, Okayama University
Minoru IZUMI
The Graduate School of Natural Science and Technology, Department of Biofunctional Chemistry, Laboratory of Applied Natural Products Chemistry, Okayama University
Hiroshi KANZAKI
The Graduate School of Natural Science and Technology, Department of Biofunctional Chemistry, Laboratory of Applied Natural Products Chemistry, Okayama University
Naomichi BABA
The Graduate School of Natural Science and Technology, Department of Biofunctional Chemistry, Laboratory of Applied Natural Products Chemistry, Okayama University
Kazuyoshi KAWAZU
The Graduate School of Natural Science and Technology, Department of Biofunctional Chemistry, Laboratory of Applied Natural Products Chemistry, Okayama University
Shuhei NAKAJIMA
The Graduate School of Natural Science and Technology, Department of Biofunctional Chemistry, Laboratory of Applied Natural Products Chemistry, Okayama University

Keywords: antinematodal activity, Bursaphelenchus xylophilus, diterpenoid, ingenane, Euphorbia kansui

JOURNAL FREE ACCESS

2007 Volume 71 Issue 4 Pages 1086-1089

DOI https://doi.org/10.1271/bbb.60677

View "Advance Publication" version (April 7, 2007).

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Abstract

Three compounds, 20-O-acetyl-[3-O-(2′E,4′Z)-decadienoyl]-ingenol (1), 20-O-acetyl-[5-O-(2′E,4′Z)-decadienoyl]-ingenol (2) and 3-O-(2′E,4′Z)-decadienoylingenol (3), were isolated from Euphorbia kansui under the bioassay-guided method. Each compound showed the same antinematodal activity against the nematode, Bursaphelenchus xylophilus, at a minimum effective dose (MED) of 5 μg/cotton ball.

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