Regulation of the Violacein Biosynthetic Gene Cluster by Acylhomoserine Lactone-Mediated Quorum Sensing in Chromobacterium violaceum ATCC 12472

Tomohiro MOROHOSHI; Katsumasa FUKAMACHI; Masashi KATO; Norihiro KATO; Tsukasa IKEDA

doi:10.1271/bbb.100385

Biochemistry & Molecular Biology Notes

Regulation of the Violacein Biosynthetic Gene Cluster by Acylhomoserine Lactone-Mediated Quorum Sensing in Chromobacterium violaceum ATCC 12472

Tomohiro MOROHOSHI, Katsumasa FUKAMACHI, Masashi KATO, Norihiro KATO, Tsukasa IKEDA

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Keywords: quorum sensing, N-acylhomoserine lactone, violacein, Chromobacterium violaceum

JOURNAL FREE ACCESS

2010 Volume 74 Issue 10 Pages 2116-2119

DOI https://doi.org/10.1271/bbb.100385

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Abstract

Chromobacterium violaceum produces the purple pigment violacein by quorum-sensing regulation. 20-bp of the lux box-like sequence was found upstream of vioA in C. violaceum ATCC 12472. CviR received C10-HSL and C6-HSL and activated the transcription of vioA in Escherichia coli. However, in strain ATCC 12472, C6-HSL inhibited both C10-HSL-mediated violacein production and the transcription of vioA.

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