Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Biochemistry & Molecular Biology Notes
Transient Up-Regulation of Immunity- and Apoptosis-Related Genes in Caco-2 Cells Cocultured with THP-1 Cells Evaluated by DNA Microarray Analysis
Yoko ISHIMOTOYuji NAKAIHideo SATSUMamoru TOTSUKAMakoto SHIMIZU
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JOURNALS FREE ACCESS

2010 Volume 74 Issue 2 Pages 437-439

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Abstract

We analyzed changes in gene expression in Caco-2 cells cocultured with THP-1 cells over time periods of 0, 1, 3, 6, 24, and 48 h using a DNA microarray. Differentially expressed genes extracted with maSigPro indicated that an early defense response and cell death occured at the same time, causing an inflammatory condition.

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© 2010 by Japan Society for Bioscience, Biotechnology, and Agrochemistry
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