Gene Expression of Inflammatory Cytokines in Peripheral Leukocytes in db/db Mice Rose with Progression of Diabetes

Saki FUJIMOTO; Kazuki MOCHIZUKI; Toshinao GODA

doi:10.1271/bbb.100149

Food & Nutrition Science Notes

Gene Expression of Inflammatory Cytokines in Peripheral Leukocytes in db/db Mice Rose with Progression of Diabetes

Saki FUJIMOTO, Kazuki MOCHIZUKI, Toshinao GODA

著者情報

キーワード: diabetes, inflammatory cytokine, peripheral leukocyte, db/db mice

ジャーナルフリー

2010 年 74 巻 7 号 p. 1488-1490

DOI https://doi.org/10.1271/bbb.100149

View "Advance Publication" version (July 7, 2010).

詳細

抄録

Fourteen-week-old db/db mice showed significant higher blood glucose levels than 7 week-old mice. The mRNA levels of IL-1β and S100a4/a6/a9 in peripheral leukocytes were higher in 14 week-old mice than in 7 week-old mice. Together, inflammatory cytokine/cytokine-like factor mRNA levels in peripheral leukocytes were associated with progression of diabetes in db/db mice.

責任著者(Corresponding author)

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