Gene Expression of Inflammatory Cytokines in Peripheral Leukocytes in db/db Mice Rose with Progression of Diabetes

Saki FUJIMOTO; Kazuki MOCHIZUKI; Toshinao GODA

doi:10.1271/bbb.100149

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Gene Expression of Inflammatory Cytokines in Peripheral Leukocytes in db/db Mice Rose with Progression of Diabetes

Saki FUJIMOTO, Kazuki MOCHIZUKI, Toshinao GODA

著者情報

キーワード: diabetes, inflammatory cytokine, peripheral leukocyte, db/db mice

ジャーナルフリー早期公開

論文ID: 100149

DOI https://doi.org/10.1271/bbb.100149

この記事には本公開記事があります。

The final version of this article is now available: Vol. 74 (2010) , No. 7 p.1488

詳細

抄録

Fourteen-week-old db/db mice showed significant higher blood glucose levels than 7 week-old mice. The mRNA levels of IL-1β and S100a4/a6/a9 in peripheral leukocytes were higher in 14 week-old mice than in 7 week-old mice. Together, inflammatory cytokine/cytokine-like factor mRNA levels in peripheral leukocytes were associated with progression of diabetes in db/db mice.

責任著者(Corresponding author)

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