Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Food & Nutrition Science Note
Hepatic Oxidoreduction-Related Genes Are Upregulated by Administration of Hydrogen-Saturated Drinking Water
Yuji NAKAIBunpei SATOShota USHIAMAShinji OKADAKeiko ABESoichi ARAI
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JOURNAL FREE ACCESS

2011 Volume 75 Issue 4 Pages 774-776

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Abstract

The effects of the administration of molecular hydrogen-saturated drinking water (hydrogen water) on hepatic gene expression were investigated in rats. Using DNA microarrays, 548 upregulated and 695 downregulated genes were detected in the liver after 4 weeks of administration of hydrogen water. Gene Ontology analysis revealed that genes for oxidoreduction-related proteins, including hydroxymethylglutaryl CoA reductase, were significantly enriched in the upregulated genes.

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© 2011 by Japan Society for Bioscience, Biotechnology, and Agrochemistry
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