Increasing Effect of an Oral Intake of <small>L</small>-Hydroxyproline on the Soluble Collagen Content of Skin and Collagen Fragments in Rat Serum

Mami AOKI; Kouzou SUTO; Miho KOMATSU; Ayako KAMIMURA; Koji MORISHITA; Motoo YAMASAKI; Toshifumi TAKAO

doi:10.1271/bbb.120058

Food & Nutrition Science Notes

Increasing Effect of an Oral Intake of L-Hydroxyproline on the Soluble Collagen Content of Skin and Collagen Fragments in Rat Serum

Mami AOKI, Kouzou SUTO, Miho KOMATSU, Ayako KAMIMURA, Koji MORISHITA, Motoo YAMASAKI, Toshifumi TAKAO

著者情報

キーワード: oral intake, L-hydroxyproline, collagen

ジャーナルフリー

2012 年 76 巻 6 号 p. 1242-1244

DOI https://doi.org/10.1271/bbb.120058

詳細

抄録

We examined the effects of oral L-hydroxyproline (Hyp) on collagen in the body. After 2 weeks' administration of Hyp (0.5 or 1 g/kg) to F344 male rats, the soluble collagen content of the skin had increased, and the serum concentration of collagen peptides was correlated with the skin content of soluble collagen. This result suggests that oral Hyp augmented collagen metabolism.

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