Dietary Coenzyme Q10 Suppressed Hepatic Hydroxymethylglutaryl-CoA Reductase Activity in Laying Hens

Kazuhisa HONDA; Takaoki SANEYASU; Tohru MOTOKI; Yuriko PARK; Hiroshi KAMISOYAMA

doi:10.1271/bbb.130039

Food & Nutrition Science Notes

Dietary Coenzyme Q10 Suppressed Hepatic Hydroxymethylglutaryl-CoA Reductase Activity in Laying Hens

Kazuhisa HONDA, Takaoki SANEYASU, Tohru MOTOKI, Yuriko PARK, Hiroshi KAMISOYAMA

著者情報

キーワード: coenzyme Q10, ubiquinone, egg yolk, cholesterol

ジャーナルフリー

2013 年 77 巻 7 号 p. 1572-1574

DOI https://doi.org/10.1271/bbb.130039

View "Advance Publication" version (July 7, 2013).

詳細

抄録

The effects of dietary coenzyme Q10 (CoQ10) on cholesterol metabolism in laying hens were investigated. Dietary CoQ10 significantly reduced egg yolk cholesterol content and suppressed hepatic hydroxymethylglutaryl-CoA reductase (HMGR) activity. It is therefore likely that CoQ10 acts as an HMGR inhibitor in the livers of laying hens, which in turn results in a reduction in egg-yolk cholesterol.

責任著者(Corresponding author)

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