The Vagotomy Alleviates the Anorectic Effect of an Excess Amount of Dietary Leucine on Rats Fed a Low-Protein Diet

Ryoji YOSHIMURA; Yee Yin HO; Takafumi MIZUSHIGE; Kousaku OHINATA; Ryuhei KANAMOTO

doi:10.1271/bbb.130150

Bioscience, Biotechnology, and Biochemistry

Online ISSN : 1347-6947
Print ISSN : 0916-8451

Food & Nutrition Science Notes

The Vagotomy Alleviates the Anorectic Effect of an Excess Amount of Dietary Leucine on Rats Fed a Low-Protein Diet

Ryoji YOSHIMURA, Yee Yin HO, Takafumi MIZUSHIGE, Kousaku OHINATA, Ryuhei KANAMOTO

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Keywords: excess leucine, vagotomy, rat, anorectic effect, low-protein diet

JOURNAL FREE ACCESS

2013 Volume 77 Issue 7 Pages 1593-1594

DOI https://doi.org/10.1271/bbb.130150

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Abstract

It is well known that large dose of leucine reduces the food intake and causes growth retardation in experimental animals when leucine is given with a low-protein diet. However, the mechanism for the anorectic effect of leucine has not yet been clarified. We demonstrate here that the anorectic effect of leucine was significantly reduced in a vagotomized rat.

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