Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451

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Wx/ae Double-Mutant Brown Rice Prevents the Rise in Plasma Lipid and Glucose Levels in Mice
Kenji MATSUMOTOMasashi MAEKAWAMakoto NAKAYAHatsuho TAKEMITSUHikaru SATOHShinichi KITAMURA
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ジャーナル フリー 早期公開

論文ID: 120501

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Wx/ae is a novel rice cultivar generated by crossing waxy mutant and amylose-extender mutant rice cultivars. Wx/ae brown rice contains highly beneficial nutrients for lipid and glucose metabolism, including resistant starch, dietary fiber, and γ-oryzanol, when compared to Koshihikari brown rice, the non-waxy japonica cultivar. To examine the effects of wx/ae brown rice on glucose and lipid metabolism, type 2 diabetic NSY/Hos mice were fed a high-fat diet containing 25% of wx/ae brown rice or Koshihikari brown rice for 10 weeks. The plasma total cholesterol, non-high-density lipoprotein cholesterol, triglyceride, and non-esterified fatty acid levels of the wx/ae group were significantly lower than those of the Koshihikari group. Moreover, the fasting blood glucose level and pathological score of glycosuria of the wx/ae group were also significantly lower than those of the Koshihikari group. These results indicate that wx/ae brown rice has the potential to prevent the rise in plasma lipid and glucose levels.
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© 2012 by Japan Society for Bioscience, Biotechnology, and Agrochemistry
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